Background:
Childhood vaccination is a widely used strategy to reduce the population impact of vaccine-preventable diseases. Some social circumstances can significantly affect the coverage and achievements of immunization programs.

Objective:
Determine vaccination coverage before and after the pandemic in children under 6 years old in the Cartagena district.

Methods:
A descriptive study was performed. The vaccination coverage of the biologics included in the national vaccination program was evaluated. A total of 3,829 boys and girls under 6 years old were included, using random cluster sampling. Two coverage measurements were made: one in 2019 and one in 2022. Descriptive statistics were applied to the data.

Results:
The highest vaccination coverage is presented in the newborn doses (Anti-tuberculosis (BCG) and Anti-hepatitis B) with 99.6% for the year 2019 and 100% for the year 2022. The biologicals with the lowest coverage are the 5-year reinforcements (Antipolio and reinforcement against Measles, Rubella and Mumps), with percentages of 68.4% and 69.3% respectively. In all the biologicals, a coverage reduction of 11% on average is observed for the year 2022. The main reason for not vaccinating is the lack of time for parents and caregivers to attend consultations, mainly due to the restrictions derived from the COVID 19 pandemic.

Conclusion:
Vaccination coverage depends on the availability of parents and caregivers to attend the consultations. A greater impact due to the restrictions of the COVID 19 pandemic is observed.