Brief outline of the overall workshop: Strong and robust primary health care (PHC) models are able to address the majority of population health needs close to people’s homes. Evidence shows that improved collaborative practices among PHC professionals, in particular, effectively contribute to meet complex needs of the increasing number of people with chronic conditions and vulnerable groups while ensuring continuous care. In the last decade, strengthening the nursing profession as part of collaborative interprofessional PHC teams has been a promising approach to further evolve PHC models. Accordingly, PHC nurses’ responsibilities and autonomy have been expanded in many countries. However, the development of Advanced Practice Nursing (APN) roles in PHC is pacing differently across different countries. In the focus of this workshop are two countries - Germany and Brazil - which have not yet implemented APN in primary care but are discussing and developing visions for APN roles. Both countries differ concerning resources, the organization of PHC, and the role of the nursing profession. However, similarities can be observed considering the vision of APN in PHC: Promising approaches in both countries build on the idea to reach beyond the sheer extension of individual care and advanced clinical tasks. They focus on strengthening family- and community-oriented PHC approaches, e.g. by conducting home visits and collective health promotion activities. In this workshop, we present Results of a study analyzing strengths, possibilities, and obstacles of APN implementation, and ultimately, new models of interprofessional collaboration in PHC in Brazil and Germany. Workshop participants are invited to discuss with us about the possibilities, chances, and challenges for both countries. In addition to that the Discussion Aims at identifying new arrangements of APN in PHC in the two countries which can be indicators for further development in other countries. Specific Aims and Objectives: The workshop presents results of an exploratory comparative study comprising of a document and literature search and focus groups with stakeholders in Brazil and Germany. Building up on the study results, workshop participants will learn and discuss different perspectives for APN development and collaboration in PHC and identify future research needs. The key questions that the workshop will address: What are strengths, possibilities, and obstacles of APN implementation, and consequently, new models of interprofessional collaboration in PHC in Brazil and Germany? What conditions enable or hinder APN development in Brazil and Germany? How can APN roles contribute to a more community-oriented PHC? Which research is needed in the context of APN development in PHC?