Introduction and Objectives: The project in question is part of various interventions already defined at national and regional level regarding the management of chronicity and multichronicity. Chronic pathologies are progressively growing and, requiring continuity of assistance for long periods of time as well as a strong integration with social services, they use up a large part of the resources of the SSR. Chronic-degenerative diseases weigh on the daily lives of four out of ten Italians. Methods: The criteria for monitoring the evolution of the severity of the state of health will be defined and innovative tools will be defined that are useful for identifying the chronic population in a condition of serious frailty that requires greater social-health care. The system will have to make it possible to modify the diagnostic therapeutic assistance approach according to the seriousness of the social context in which the patient has fallen through pathology-specific integrated assistance programs - Disease management programs - based on the Chronic Care Model (CCM), developed for partially obviate the financial and organizational fragmentation of the health service and try to bridge the gap between the abundance of resources employed, services provided and the relative shortage of health outcomes. Conclusions: 1. The project idea that we intend to present concerns the implementation of a modern telemedicine system aimed at patients suffering from chronic diseases. The telemedicine module is of fundamental importance, as it allows remote clinical screening of all those patients with chronic and multichronic pathologies, in order to avoid hospitalization of the patients themselves. 2. This project also involves the use of an Augmented Reality Device that allows you to interact with holograms in the physical environment. With this approach, the way of thinking about telemedicine changes completely.