Background: Precision (or personalized) medicine is defined as the application of emergent technologies to better manage patients’ health and to target therapies to achieve the best outcomes in the management of a patient’s disease or predisposition to disease. Used properly, precision medicine should both improve patient outcomes and deliver benefits to the health service - including reducing the cost of ineffective treatment and multiple tests. To bring precision medicine in to reality, we need to understanding the relevant regulatory issues within precision medicine, exploring opportunities that could further improve patient safety and outcomes, identifying issues for the state to monitor, and putting forward recommendations that would continue to support innovation. How we move from our current healthcare system to a precision medicine system is the challenge we face. We can chase how others in the world develop and implement precision medicine, primarily as a race to be first in biomedical and genomic discovery; or we can lead the world in demonstrating how precision medicine should be responsibly and sustainably delivered. Given the tools and increased insight into health and disease, precision medicine offers tremendous opportunity to help address many of the barriers and challenges in patient’s management. Precision medicine offers the ability to understand and reduce individual risk for developing various health concerns. This can support better decision-making about where to focus prevention efforts. It is well recognized that behavior change is an important aspect of many treatment plans, and also one of the most difficult. Through increased data and real time feedback, there is the potential to support more individualized behavior change that is more suited to the individual rather than a generic education program. Additionally, rather than the trial and error of therapies that are often experienced, precision medicine approaches, based on biological drivers, should be able to provide earlier diagnosis, preventing months or years of provider visits and tests, and can lead to earlier treatment and prevention of complications. Not only is there a potential to provide an earlier diagnosis, there is great potential to predict, based on use of large data sets, which intervention is most likely to achieve the desired outcomes with the fewest side effects. This has the potential to save treatment costs as well as reduce suffering and complications. The workshop session will bring comprehensive perspectives from government, hospital leader, and clinician to apply the precision medicine from theory in to practice. Workshop participants will identify how to implement precision medicine as what best fit to their field of expertise.