Background: Pesticides exposure(16.70%,12.91%);food poisoning(30.05%,35%),traditional medicine intoxication(10.85%,14%),ingestion of unknown substances (13%,16.9%),household products(3.5%,7%),suicide attempts with hydrogen sulfur(6%,0%).Clinically, patients had trouble breathing, nausea, vomiting, diarrhea and confusion. Among hospitalized patients,18.65% developed kidney failure and liver problems.85% delayed in consulting. Of 276 interviewed participants,46% reported they experienced poisoning in their life.65% consulted traditional healers.24% consulted modern health professionals,11% didn’t consult. Conclusions: There is a high incidence of food poisoning and ingestion of unknown substances in rural communities than in urban areas, in children than adults.The negative behavior of patients in seeking healthcare leads to diseases chronicity causing several preventable complications and an increase of death rate. Raising awareness and establishing poisoning control centers are essential to prevent and control threats associated with poisoning.