Background and Objectives: Interprofessional education (IPE) is a unique model of educating students for careers in the health sector, where collaboration and teamwork are critical skills required to maximally address the health needs of society. However, it seems that the words, “collaboration” and “teamwork” in the IPE concept is often preferentially (mis)applied, to suggest collaboration and teamwork with mostly professionals within the clinical/institutional setting and does not usually include other “professionals” associated with the health system. This paper highlights the need to broaden and diversify the operational definition and application of IPE to emphasize collaboration and teamwork with extra-professionals, super-professionals and the supra-professional to optimally and holistically address the health needs of the community to ensure universal health coverage. Methods: This is a conceptual paper. Results: The health system is bigger than the healthcare subsystem. Therefore, interprofessional education should not only be about the professionals in the field of medicine or nursing or medical laboratory science but also other professionals involved in “addressing the priority health concerns of the community, region, and/or nation they have a mandate to serve.” Collaboration and teamwork with extra-professionals, super-professionals and the supra-professional are key to addressing human health needs at both the institutional, clinical and community levels. Conclusions: There is a missing link in the definition and operationalization of the concept of interprofessional education. The health sector is complex, diverse and encompasses other professionals, thus, requiring health professionals to work together with other stakeholders (particularly communities and policy makers) to effectively and efficiently provide need-based health to Africans. There is the need to broaden and diversify the operational definition and application of interprofessional education of students to emphasize collaboration and teamwork with extra-professionals, super-professionals and the supra-professional to optimally and holistically address the health needs of the community and to ensure universal health coverage.