Material and methods:
Shingles vaccine was administered at the vaccination center afferent to the Hospital Hygiene, thanks to an agreement of it with the operative units that manage particularly frail patients to improve vaccination coverage, to reduce vaccine hesitancy and offering therapeutic continuity. Tailored vaccination pathways have been created for “ fragile” patients such as patients with HIV, patients with inflammatory bowel disease (IBD) and patients splenectomized or to undergo splenectomy.

Results:
We administered a total of 143 doses whereof 64.58% in patients with IBD, 18.06% with HIV, 4.08% patients with splenectomy and the remaining part patients with over 65 years old.

Discussion and conclusion:
It is necessary to alert policy makers about the need to operationalize the vaccination indications for frail/immunocompromised individuals contained in the PNPV 2017-2019 as well as in the recommendations expressed by several guidelines. Vaccination coverage of these individuals is in fact very low to date. It is deemed necessary to act with a sense of urgency with actions aimed at fostering new vaccination pathways, closer to the places where patients attend for disease treatment.