Background:and Objectives: Cervical, breast, and colon cancer screening programs are included in preventive health practices in Turkey. Cancer screening for the population in the risk group can contribute to the reduction of morbidity and mortality through early diagnosis. This study aimed to evaluate the knowledge, attitudes, and behaviors of individuals over 30 living in a district with a cancer screening center in Istanbul toward current cancer screening programs. Methods: The cross-sectional type of research was carried out between 05.04.2022 and 19.04.2022 by face-to-face survey method. The universe of the research was determined as 210 people selected from individuals aged 30 and over living in the chosen district using the World Health Organizations rapid assessment system, 30x7 clustering method. Results: The research was carried out with a total of 159 (75.7%) volunteers. The mean age of the participants was 49.2±13.4%, and 50.9% (n=81) were women. 56% (n=89) of the participants stated that they knew that there was a cancer screening center in their district, and 10.7% (n=17) stated that they were informed about cancer screening methodsby their family physicians.. 32.1% (n=51) of the participants had previously had any cancer screening. Among the individuals in the age group where screening is recommended; 23.5 % (n=16) of individuals had a colonoscopy, 21.2% (n=14) had stool occult blood test, 75.9 % (n=41) had a mammography examination for breast cancer, 67.9% (n=4) for cervical cancer 53) had smear test, 9.1% (n=7) had HPV DNA tests they had it done. Conclusions:This study showed that although access to the cancer screening center is easy and free in terms of physical conditions, the rates of colon and cervical cancer screening are low. Referring individuals at risk of colon, cervix, and breast cancer to cancer screening by family physicians may contribute to an increase in cancer screening rates.