ackground: The changes in peoples lifestyle during the COVID-19 pandemic due to the confinement assigned in different countries caused different mental health problems, so it is important to identify the consequences once this stage is over. Objective: To determine the association between confinement and the presence of post-Covid-19 pandemic anxiety. Methods: A cross-sectional, prospective study was carried out between January and April 2022, three months after return to usual activities free of confinement, including men and women aged between 18 and 50 years, residents of the city of Veracruz, excluding participants with already diagnosed psychological disorder, such as depression or anxiety. A survey was applied through Google Forms, including the Beck anxiety scale (Cronbachs alpha 0.90). SPSS v22 software was used for data analysis, Chi square test with Odds Ratio (OR) and 95% confidence interval (95%CI), assigning statistical significance with p0.05 when comparing between people with and without anxiety. Conclusions: The presence of anxiety during the current post-pandemic stage of COVID-19, where the indication of mandatory confinement has been withdrawn, is not associated with the different behaviors carried out during the mandatory confinement stage. Key: Anxiety is a disease that increased during the confinement stage, which, apparently, can be recovered shortly after the withdrawal of this measure. It´s essential to be able to generate knowledge and be able to provide comprehensive care to the population in the event of a new epidemic.