Background and Objective: A diabetic patient has an increased risk of developing invasive infectious diseases caused by micro-organisms such as Influenza Virus and Streptococcus Pneumoniae or serious complications. This risk can be drastically reduced through vaccination. Preventing infectious diseases through vaccinations is a milestone of public health; hence it is essential to investigate vaccination coverage in our target population. The main objective of our study is to analyze the adherence to anti-influenza and anti-pneumococcal vaccinations in the diabetic patient population. Secondly, the coverage of vaccines between age groups was examined with particular attention to completed and partial vaccination courses. Methods: The population was analyzed through the interrogation of the Regional Epidemiological Repository and subsequent analysis. Diabetics residents from 01/01/2002 to 30/04/2022 were studied. Results: The statistical analysis of diabetic patients (32 500 subjects) highlights a full pneumococcal vaccination coverage (sequential schedule) of 16.46%; partial coverage tantamount to 36.75% and 46.79% of patients not vaccinated for Pneumococcus. On the subject of influenza coverage in the target population, we see a complete coverage (annual vaccination carried out) of 47.25%; partial (at least one vaccination from the date of diagnosis) equal to 31.2% and 21.55% of subjects are not vaccinated at all for influenza. It also emerges that 5% of diabetic patients have no known vaccination history in the regional vaccine service. Conclusions: Our analysis underlines that a considerable part of the target population does not have adequate protection from the disease because 83.54% of patients have a partial or absent course against Pneumococcus and 52.75% of cases have a partial or absent course against influenza. Our study will continue by evaluating the impact of COVID-19 pandemic on our target vaccination coverage. In conclusion, it is considered essential to undertake mop-up and catch-up strategies to implement the current coverage in the diabetic population.